Prince Charles lashed out at climate change sceptics, saying they are playing "a reckless game of roulette" with the planet's future.
Sceptics are having a "corrosive effect" on public opinion, Charles added.
"Their suggestion, that hundreds of scientists around the world are somehow unconsciously biased, creates the implication that many of us are secretly conspiring to undermine and deliberately destroy the entire market-based capitalist system," he said.
Many doubters particularly in the United States have dismissed scientific evidence supporting warming of the earth due to human activity, arguing that the large majority of scientists are wrong, or the consequences of warming overstated.
Charles asked: "How are these people going to face their grandchildren and admit to them that they failed their future?"
Along with top officials of the European Union, Charles was addressing the Low Carbon Prosperity Summit, a conference devoted to engaging more European businesses in promoting a low-carbon economy.
In a speech to a packed European Parliament chamber, Charles touched on topics ranging from the need to protect fisheries and the Amazon rain forest, to making low-carbon emissions affordable and competitive.
Charles, who has been active in promoting environmental issues, was asked to participate in the conference in order to raise public awareness throughout Europe.
"Your presence brings added value and attention to this important issue," EU President Herman Van Rompuy said.
The prince is a patron of the Cambridge Program for Sustainability Leadership, which works with business, government and civil society to promote a sustainable economic future.
Sir Michael Black-Feather the English first minister said that he fully agreed with his Royal Highness Prince Charles. Sir Michael went on to say the trouble is that many think of Charles as a delusional as many grate man are seen by those that can’t see what is to come in our futures, and by the time when their true genius is seen it sometimes becomes too late. I remember once after seeing the first start trek TV show staring Williams Shatner back in 1966, I was eight years old, and I said to other children at school the next day when we were talking about it, being the biggest things since 1963 Doctor Who, I said that one day the communication devices that they had we would all have one, one-day in are pockets talking to each other all over this world and sending pictures and information, I was laugh at called a nut case and made to look the fool in front of the whole school, now I have such a device in my pocket and so do many of you?.